Eccema dishidrótico palmoplantar asociado a secukinumab

A Case Report of Transgrediant Palmoplantar Keratoderma (Mal de Meleda)

Mal de Meleda is a rare autosomal recessive transgredient keratoderma .Onset is in early childhood, and the development of hyperkeratosis is preceded by erythema. Patches of waxy ivory-yellow hyperkeratosis extend across the whole palms and soles, and on to the dorsal surfaces of hands and feet. Similar lesions of knees and elbows may develop. We describe an 18 year old man with the diagnosis o...

Brunauer-Fuhs-Siemens palmoplantar keratoderma: A rare, striate type of focal palmoplantar keratoderma

Brunauer-Fuhs-Siemens palmoplantar keratoderma, commonly known as striate palmoplantar keratoderma, is a rare, autosomally inherited disease of linear hyperkeratosis in which patient usually presents with conspicuous longitudinal hyperkeratosis on volar surface of hands and feet. Mutations in 3 genes namely desmoglein 1, desmoplakin and keratin 1, have been identified and held responsible for t...

Erosive Palmoplantar Lichen Planus

Erosive palmoplantar lichen planus (LP), also known as ulcerative or bullous LP, was first described by Cram et al. in 1966 as a rare variant of LP that can affect mucous membranes, palms, and soles. It presents clinically as erythematous, ulcerated plaques that run an extremely chronic course and are resistant to all types of treatment. The patient was an 84-year-old woman with a personal hist...

[Palmoplantar hyperkeratotic plaques].

An unusual palmoplantar pigmentation.

A 60 year old man had asymptomatic progressive pigmentation of the palms (fig 1), fingertips (fig 2), and soles for the last 20 years. Besides this, he had discoloration of his sclerae (fig 3). He was well but for low backache and joint pains of a few months’ duration. Histopathological examination of the skin lesion was diagnostic (fig 4). Questions (1) What is your diagnosis? (2) What are the...